They found $22,000 worth of fentanyl, $7,000 worth of cocaine and $670 cash.
The NRP searched a home and a car in St. Catharines on Tuesday, in the Niagara Street and Church Street area.
Officers were responding to a report of two men with guns, but they did not find any firearms on scene.
Three people have been arrested and charged; a 30-year-old St. Catharines woman, a 23-year-old Hamilton man and a 17-year-old boy from Hamilton.
Region Trims More from Budget
A further look by Chair Bob Gale and staff dropped the increase to 6.3%
Cold Weather Policy for Homeless Not Changing
Niagara's public health committee shown the system works
Niagara Falls Handling Salt Shortage
The city says there's a North America wide shortage
Man Killed in Tent Fire
Update: Police were called to Mountain Locks Park
Region Updated on Measles Outbreak
Health committee told more work is needed, but gave nod to health care workers for their efforts
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The city has decided to stop using the social media platform
Police Looking for Laundry Thief
They say she stole some money last month
Toronto Man Charged with Trafficking
Police made the arrest with help from Niagara Parks police, finding fentanyl and cocaine earlier this week